by Thorne Research

Nicotinamide riboside with resveratrol and cofactors all in one capsule!

  • Supports healthy aging

  • Helps regulate metabolism for improved metabolic syndrome parameters

  • Nicotinamide riboside (NR) - the most efficient direct precursor to NAD+

  • Resveratrol and quercetin increase the activity of sirtuins

  • Betaine provides important methylation factors

Product Description

Nicotinamide Riboside (NR)

  • The most direct precursor to NAD+ - it's essential for mitochondria to perform their myriad functions

  • Important in the regulation of cellular aging

  • Provides support for metabolic syndrome

NR is the most direct precursor to nicotinamide adenine dinucleotide (NAD+). The mitochondria cannot perform their crucial cellular functions without a sufficient supply of NAD+. NR offers fundamental support for mitochondrial biogenesis, as well as all other mitochondrial activities - from energy production to the regulation of metabolism and cellular aging.


  • Purely trans-resveratrol - not a diluted plant extract

  • Increases activity of the sirtuins - SIRT1 and SIRT3, in particular

  • Provides benefit for metabolism and for healthy aging

Resveratrol mimics the effect of calorie restriction by activating the sirtuin group of proteins. In one study, resveratrol was shown to be the most potent natural activator of the sirtuins. Resveratrol shows promise in helping attenuate the effects of several age-related conditions.

Quercetin Phytosome

  • Quercetin is bound to sunflower-sourced phospholipids for enhanced absorption

  • Enhances sirtuin activity

  • Slows the breakdown of resveratrol in the body

Research shows that quercetin not only acts as a potent antioxidant and is synergistic with the activities of resveratrol, it also slows the breakdown of resveratrol in the body. Like resveratrol, quercetin also enhances sirtuin activity.


  • Important methyl donor

  • Provides nutrient support for fatty liver

  • Supports homocysteine metabolism

Betaine - also known as trimethylglycine - is a premier methyl donor. In addition to providing significant methylation support because it can donate three methyl groups, betaine provides support for important metabolic functions that are associated with metabolic syndrome.

Two capsules contain: Nicotinamide Riboside Chloride 300 mg, Quercetin Phytosome (Sophora japonica concentrate (leaf) / Phospholipid complex from Sunflower) 250 mg, Trans-Resveratrol 150 mg, Betaine Anhydrous (Trimethyglycine) 50 mg.

Other ingredients: High and low viscosity hydroxypropyl methylcellulose, Leucine, MagnesiumCitrateLaurate (Time-Sorb), Hypromellose (derived from cellulose) capsule, Silicon Dioxide.

Suggested use: Take 2 capsules one to two times daily or as recommended by your health-care practitioner.

The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

60 capsules

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Dr. Ronald Hoffman

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Product information by Thorne Research

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