14 supplements you should NEVER take - updated! (part one)

By Dr. Ronald Hoffman


As you already know, I'm a big proponent of nutritional supplements. The majority of supplement manufacturers are responsible and ethical, and their claims are, by and large, science-based.

That does not mean that I suspend my critical faculties when it comes to supplements. As an active practitioner, I've had the opportunity to field-test many highly-touted health products over the years. Sometimes they don't measure up to their extravagant claims.

In an Intelligent Medicine podcast with Steve Mister, Executive Director of the Council for Responsible Nutrition, he coined a memorable phrase: "The supplement industry is a 'tale of two industries'." Regrettably, there are some players who put profits before service to consumers.
I wrote on this topic orginally last year, but in the time since have come across a few additions to the list that I thought my readers should be aware of. Here are, in my opinion, some of the worst offenders:

1) Coral Calcium: The very personification of hype, extensive advertising campaigns have pitched "Coral Calcium" as a panacea for conditions ranging from cancer to chronic fatigue syndrome. But no evidence exists for these exaggerated assertions.

There's a romantic aura about sea coral as a natural source of calcium. The truth is that it's just calcium carbonate, the cheapest and least absorbable form of calcium (I prefer calcium citrate). Also, unless chemically purified or made synthetically, harvested calcium is likely to contain high levels of contaminants like lead.

Besides, as an inveterate scuba diver, I like my coral just fine where it belongs: in the ocean.

2) Vitamin D2: Otherwise known as ergocalciferol, it's the active ingredient in most prescription vitamin D (e.g., Drisdol, Calcidiol). Some discount supplements contain Vitamin D2, even advertising it as "vegetarian D" since it's made from mushrooms, as opposed to D3, which comes from sheep lanolin (technically "cruelty-free" because the sheep are shorn for wool anyway).

Studies now confirm that D2 is only about 60% as bio-available as D3; moreover, it's been theorized that excess D2 may cancel out D3's benefits. Vitamin D2 should not be regarded as a nutrient suitable for supplementation or fortification, yet it continues to be sold.

3) "Flush-Free" Niacin: Vitamin B3 in the form of niacin commonly causes uncomfortable flushing. The effect is transient and harmless, but it can be disconcerting.

Unscrupulous manufacturers offer consumers "flush-free" niacin, which is inositol hexanicotinate. I've tried it on patients, and it never seems to work to lower cholesterol.

Even more disconcerting are recent studies that suggest that, while high-dose regular niacin can lower cholesterol and raise HDL, this doesn't translate into meaningful protection against heart disease and stroke. The suggestion is that it may not just be about cholesterol.

4) Policosanol: A derivative of sugar cane, policosanol was claimed by Cuban researchers to be very effective for reducing cholesterol. But when Scandinavian researchers tried to replicate the Cubans' results, policosanol came up short. My take? Policosanol is a lame attempt by Cubans to boost their foreign exchange.

5) Raspberry ketones: Promoted as a "fat-burners in a bottle," raspberry ketones actually possess meager scientific bona fides.

NO scientific studies have been performed on humans. The few studies that exist were done on rodents and were small in size and published in obscure Asian journals. One test-tube study showed favorable metabolic changes when cells were exposed to raspberry ketones, but in vitro results often don't translate to real live people. Dr. Oz recently was burned for his too-enthusiastic embrace of this dubious product.

6) 3-6-9: These healthy fatty acid supplements are said to provide a balanced blend of Omega-3, 6, and 9 oils. But most people have too many Omega-6 fatty acids already, and Omega 9 oils can best be obtained by consuming extra-virgin olive oil, which offers the additional benefit of healthy polyphenols.

The business end of these supplements are the Omega-3 oils which are usually more costly than Omega-6 and 9, hence it's to the manufacturer's advantage to convince you that you need all 3 in a combo pill. With all that cheap Omega-6 and 9 crammed into your capsules, there's little room for meaningful amounts of the high-quality EPA and DHA that you need.

Bottom line: Just take a high-quality fish oil supplement, and let your diet provide you with healthier, more economical natural sources of Omega-6 and 9.

7) Potassium: Studies show that one of the problems with the modern diet is that we have an increased ratio of dietary sodium to potassium. Over-the-counter potassium pills are limited by regulation to contain no more than 99 milligrams, because excess potassium can be a problem for people with poor kidney function (prescription potassium delivers more).

By comparison, a banana yields 425 mg, a baked potato with skin 925 mg. Fresh fruits and vegetables are generally rich sources of potassium, packed with healthy additional nutritional factors.

What about potassium gluconate supplements that advertise 550 mg of potassium? Actually, that's slight-of-hand: potassium gluconate is a heavy molecule, of which only about 20% is elemental potassium--1 pill delivers only 90 mg of potassium, just under the legal threshold. A mere cup of ordinary lettuce delivers more.

As you can see, things are not always all they're touted to be in the supplement world, and it's important to be sure the supplements you do take have ample research to back up their efficacy and safety. Next week, I'll share with you seven more supplements that don't make the cut.

ADD/ADHD (Attention Deficit Disorder, Hyperactivity)

  • In bad taste: the MSG symptom complex
  • Book review: The Crazy Makers
  • What are EPA/DHA?
  • Omega-3 fatty acids from fish oils
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  • 10 tips for surviving allergy season
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  • 18 supplements that may stave off Alzheimer's
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  • 6 crucial lifestyle hacks for women with DCIS breast cancer (part two of series)
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  • Dr. Nicholas Gonzalez: In Memoriam
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  • Natural treatment for prostate cancer: How changing your lifestyle could save your life
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  • Something fishy this way comes . . .
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  • Advice to Tom Hanks
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  • How does Dr. Hoffman treat metabolic syndrome?
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  • General nutrition

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  • Functional food science
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  • Drugs that steal
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  • 12 drugs you should never take (part 2 of 3)
  • 12 supplements you should NEVER take
  • "Death by food pyramid": a review
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  • "Fed Up": A movie review
  • Intelligent Medicine Bone Health Protocol available now!
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  • 11 reasons why you should be using extra virgin olive oil
  • 11 things worth trying if you suffer from tinnitus
  • 12 drugs you should never take (part 1 of 3)
  • 12 drugs you should never take (part 3 of 3)
  • 12 supplements you should NEVER take
  • 13 tips for surviving the holidays (part one)
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  • 16 reasons to go nuts for nuts
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  • 6 new products that I'm excited about in 2015
  • A nerd in the kitchen: My review of The Food Lab: Better Home Cooking Through Science by J. Kenji Lo
  • American Heart Association doubles down on outmoded saturated fat recommendations
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  • Confessions of an EX-vegan
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  • How a raw foods diet can make you sick
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  • Iron: Do you want to hear the good news or the bad news first?
  • Is fructose really that bad for you?
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  • Is the way to a (wo)man's heart through his(her) stomach?
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  • Is the Whole30 diet right for you? (part two)
  • Is your grill killing you? Your personal anti-AGEing program
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  • Paleo pitfalls
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  • Pro-vegan website outs apostate meat-eaters
  • Repeat after me: "Hunger is my friend!"
  • Rethinking Super Size Me: Is it a Big Whopper?
  • Rethinking breakfast
  • Revisiting salt intake - are you eating too much or too little?
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  • What do Bill Gates, eggs, and soylent green have in common?
  • What week is it, kiddies? Why, it's National Folic Acid Week!
  • Why I liberally indulge in high-test chocolate
  • Why you don't have to feel guilty about those Valentine's Day chocolates
  • Why you should keep taking your supplements
  • Will the "real" China study please stand up
  • Yet more reasons to go gluten-free
  • GERD

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  • Antacids -- not the anti you think they are
  • Mastic gum
  • Candida
  • How to reduce your dependency on acid-blocking meds - or eliminate them entirely!
  • NEWSFLASH: Heartburn not caused by excess acidity!
  • The 7 best supplements for GERD sufferers
  • Gluten intolerance

  • Candida
  • Is gluten intolerance bullsh*t?
  • Headaches and migraines

  • Headaches: hunting down the cause of your pain
  • Headaches
  • Glucose tolerance test (GTT) - Why do I need a GTT?
  • Healthy hair

  • Healthy hair
  • What's new on the hair re-growth horizon?
  • Heart disease

  • Mitral valve prolapse
  • Chelation
  • What are EPA/DHA?
  • Omega-3 fatty acids from fish oils
  • Fatty liver disease
  • Heart disease: Are modern lifestyles at fault?
  • 20 risks for heart disease you didn't know you had
  • Intelligent Medicine Shorts:
  • 12 natural ways to protect your heart and lower your CRP
  • American Heart Association doubles down on outmoded saturated fat recommendations
  • Bergamot: A promising new cardio-protective nutraceutical
  • Bush's unnecessary stent--but wait folks, there's more!
  • Can a low-salt diet actually be BAD for you?
  • Carnitine in the cross-hairs: a fishy tale?
  • Everything you need to know about the new cholesterol guidelines
  • Former President G.W. Bush stampeded into undergoing a stent operation
  • Is the way to a (wo)man's heart through his(her) stomach?
  • Natural compounds that reduce cholesterol
  • NSAIDs increase heart risk: Now what for osteoarthritis pain?
  • Testosterone bad for men's hearts? so not!
  • The breakthrough $200,000 per year drug that prevents heart attacks (but can lead to fatal infection
  • The truth about fish oil
  • Vitamin D
  • When it comes to heart disease, can lifestyle overcome bad genes?
  • How does Dr. Hoffman treat crohn's and ulcerative colitis?

    How does Dr. Hoffman treat osteoporosis?

    Hypertension

  • Alternative approaches to hypertension
  • Chelation
  • High blood pressure
  • 20 natural ways to lower your blood pressure
  • 25 Supplements for high blood pressure (part one)
  • 25 Supplements for high blood pressure (part two)
  • Can a low-salt diet actually be BAD for you?
  • Overnight, half of American adults were reclassified as hypertensive: Is it Diagnosis Creep?
  • Vitamin D
  • What's the right diet for high blood pressure?
  • Hyperthyroid

  • Grave's disease: a nutritional approach
  • Hypoglycemia

  • Hypoglycemia
  • Glucose tolerance test (GTT) - Why do I need a GTT?
  • How sweet it is: an examination of alternatives to sugar
  • Sugar disease
  • Hypothyroidism

  • Doctors' panel doubles-down on recommendation for only synthetic thyroid for hypothyroidism
  • Hypothyroidism
  • The truth about thyroid function that doctors always seem to get wrong
  • The ugly truth emerges about synthetic thyroid medication
  • IBD

  • Addressing inflammatory bowel disease
  • Candida
  • Inflammatory bowel disease update
  • What are EPA/DHA?
  • Crohn's disease and ulcerative colitis
  • Omega-3 fatty acids from fish oils
  • One patient's UC success story
  • Do you have SIBO (Small Intestinal Bacterial Overgrowth)?
  • Do you have SIBO (Small Intestinal Bacterial Overgrowth)?
  • Do you have SIBO (small intestine bacteria overgrowth)?
  • How does Dr. Hoffman treat crohn's and ulcerative colitis?
  • Inflammatory bowel disease: What is it and what causes it?
  • Natural treatment options for inflammatory bowel disease
  • IBS

  • Irritable bowel syndrome
  • Bowelsoothe
  • Candida
  • Do you have SIBO (Small Intestinal Bacterial Overgrowth)?
  • Do you have SIBO (Small Intestinal Bacterial Overgrowth)?
  • Do you have SIBO (small intestine bacteria overgrowth)?
  • Liver disease

  • 21 ways to save your liver!
  • 21 ways to save your liver!
  • 21 ways to save your liver!
  • Fatty liver disease
  • Hepatitis
  • Menopause

  • Natural hormones: longevity drugs of the future
  • Estrogen dominance syndrome
  • Hormone replacement therapy; a closer look
  • Mitral valve prolapse

  • Mitral valve prolapse
  • Glucose tolerance test (GTT) - why do I need a GTT?
  • Omega-3 fatty acids from fish oils
  • What are EPA/DHA?
  • Optimization

  • Anti-aging medicine
  • Reflections on "health"
  • Growing older and memory
  • 12 drugs you should never take (part 2 of 3)
  • 13 reasons why most health studies are wrong
  • 13 tests your doctor is not likely to offer, but you should ask for anyway
  • 14 supplements you should NEVER take - updated! (part one)
  • 9 things your doctor doesn't know about supplements (but definitely should)
  • Want to live longer? Here's how!
  • What's your Health IQ? Take this test to find out!
  • "Don't take your vitamins"? So not!
  • "Don't take your vitamins?" so not!
  • Intelligent Medicine Bone Health Protocol available now!
  • Intelligent Medicine Health News Review
  • Intelligent Medicine Shorts:
  • 10 epic medical fails: Bet most of you have fallen for at least one! (Part one)
  • 10 responses to supplement naysayers
  • 10 things I got right 30 years ago
  • 10 ways the foods you eat can affect your sex life
  • 11 ways you can predict how long you'll live
  • 12 drugs you should never take (part 1 of 3)
  • 12 drugs you should never take (part 3 of 3)
  • 12 supplements you should NEVER take
  • 13 holiday survival tips
  • 13 tips for surviving the holidays (part one)
  • 13 tips for surviving the holidays (part two)
  • 13 tips for surviving the holidays: Part One
  • 13 tips for surviving the holidays: Part two
  • 14 supplements you should NEVER take - updated! (part two)
  • 14 things YOU know better than your doctor
  • 14 things YOU know better than your doctor
  • 17 nutraceuticals that can boost your immune response
  • 18 supplements that may stave off Alzheimer's
  • 21 ways to save your liver!
  • 24 ways we should fundamentally transform our healthcare system
  • 28 things to be thankful for this Thanksgiving
  • 6 new products that I'm excited about in 2015
  • 8 reasons why the FDA's recent ban on anti-bacterial cleansers is a good idea
  • A year-end message from Intelligent Medicine
  • American Heart Association doubles down on outmoded saturated fat recommendations
  • Are some medicines stealing your brain power?
  • Beating the winter blahs
  • Book review: "the story of the human body", by Daniel E. Lieberman, Ph.D.
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  • Chill out--it may be healthy for you!
  • Click bait health reporting: I'm calling BS on these 5 health stories
  • Clinical Focus: Nicotinamide Riboside
  • Cold, painful fingertips? Try these remedies!
  • Could a vegetarian diet undermine your mental health?
  • Debating a skeptic
  • Debunking the top 7 supplement myths
  • Defensive Eating: Taming your addiction to food
  • Detox in a box
  • Diversify your exercise portfolio
  • Do you have "poor protoplasm"?
  • Do you have WWS (Work Withdrawal Syndrome)?
  • Does this plug-in make me look fat? and does it matter anyway?
  • Dr. Nicholas Gonzalez: In Memoriam
  • Exercise that I do
  • Five health victories we've already won
  • Four more drugs you should avoid
  • From wraith to warrior: Hoffman Center's Grimaldy Vargas triumphs in her first Spartan Sprint race!
  • Frontline gets it wrong about supplements
  • GMOs: a primer
  • Happy Fourth of July! Plan a health revolution, and what's in store for Intelligent Medicine
  • Happy one millionth podcast! Let's review the best of 2015 so far
  • How to protect yourself from the harmful effects of antibiotics
  • ICYMI: Dr. Hoffman's Store now available through Fullscript!
  • Innovative therapies for Multiple Sclerosis
  • Intravenous vitamin c validated by new studies
  • Iron: Do you want to hear the good news or the bad news first?
  • Is the way to a (wo)man's heart through his(her) stomach?
  • Is there really a vast conspiracy to deprive us of cures and profit off our misery?
  • Is your BBQ killing you? Your personal anti-AGEing program
  • Is your Coumadin killing you? (The remarkable potential of vitamin K to stop arterial calcification)
  • Is your doctor a psychopath?
  • Jurassic World: A parable
  • Listen to your gut: What your microbiome can tell you about your overall health
  • Medical evolution will affect you, but how?
  • Michele Obama's water advocacy based on 'murky' science, say experts
  • My foray into personalized genetic testing
  • My foray into personalized genetic testing (part two)
  • My triathlon comeback
  • Paint-by-numbers medicine (part one)
  • Part two: 10 epic medical fails you may have fallen for
  • PhytoGuard: Your 'one-stop-shop' for phytonutrient benefits
  • Pushing back on the supplement alarmists
  • Real healthcare reform
  • Repeat after me: "Hunger is my friend!"
  • Saving the VA hospitals
  • Should doctors be role models for their patients?
  • Spring detox
  • Stem Cells: Panacea or snake oil?
  • Supplement of the week: DIM
  • Tamiflu: Our first-line drug against the flu is an epic-fail
  • Test your "Health IQ" ? round three!
  • Test Your Health IQ: Round Five!
  • Test Your Health IQ: Round four!
  • The artificial sweetener controversy: who should you believe?
  • The digital revolution: health benefit or bane?
  • The five health battles we need to fight next
  • The flu shot: Does it really work, and should you get it either way?
  • The hidden toll of Harvey
  • The new intelligent medicine communications revolution
  • The roadmap for extending longevity has been discovered: Are you following it?
  • The top 10 Intelligent Medicine podcasts of 2014
  • The top 10 health news stories of 2014
  • The top 10 resolutions you can actually keep
  • The top 12 Intelligent Medicine podcasts of 2017
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  • Top 10 supplements for 2017
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  • Vacation time is here - but do you suffer from WWS (Work Withdrawal Syndrome)?
  • Vacation time is here-but do you suffer from WWS (Work Withdrawal Syndrome)?
  • Vitamins can cause cancer-REALLY??
  • What gets ignored in the pot debate: it's not good for you!
  • What week is it, kiddies? Why, it's National Folic Acid Week!
  • What's your Health IQ? Round two!
  • Who's really in charge here-you or your germs?
  • Why I've finally taken up yoga in my sixties - and why you should too
  • Why I've finally taken up yoga in my sixties - and why you should too
  • Why intravenous vitamin therapies are a mainstay of integrative practice
  • Why you should keep taking your supplements
  • Why you shouldn't get your health advice from celebrities
  • Osteoporosis

  • Natural approach to preventing osteoporosis
  • Vitamin D
  • 'A Perfect Storm for Broken Bones' or a perfect marketing pitch for osteoporosis drugs?
  • How does Dr. Hoffman treat osteoporosis?
  • Ostera, a novel approach to osteoporosis
  • Strontium for bone health
  • Overweight

  • Sugar disease
  • Obesity treatments and tax deductions
  • How sweet it is: an examination of alternatives to sugar
  • A holistic approach to weight loss
  • Book review: In Bad Taste: the MSG Symptom Complex
  • Obesity and disease risk
  • New obesity statistics
  • Epidemic of childhood obesity
  • Fatty liver disease
  • 10 reasons why it's not your fault you're fat
  • 10 reasons why it's not your fault you're fat - UPDATED!
  • 8 reasons why it's not your fault you're fat
  • Can you really "lose 40 pounds in 40 days"?
  • It's been a bad month for carbs
  • Maximizing your metabolism
  • Nutritional weapons to fight the battle of the bulge
  • Our sisyphean battle against obesity
  • Repeat after me: "hunger is my friend!"
  • Parkinson's disease

  • Parkinson's disease and glutathione
  • Prostate disorders

  • Dealing with the prostate
  • Cernilton
  • 20 supplements that men with prostate cancer need to know about (part one)
  • 20 supplements that men with prostate cancer need to know about (part two)
  • Natural treatment for prostate cancer: How changing your lifestyle could save your life
  • Sinusitis

  • Supplement of the month: xylitol
  • Candida
  • Oregacillin
  • Skin conditions

  • Candida
  • Skin disorders
  • 10 natural solutions for winter skin dryness
  • 10 natural solutions for winter skin dryness
  • 10 natural sun-care supplements you may not have heard of
  • 10 natural sun-care supplements you need to know
  • Everything you need to know about natural therapies for acne
  • Sleep

  • Healthy sleep: recharging your batteries
  • Common sleep problems and solutions
  • Sleep update 2007
  • Stroke and TIA's

  • Chelation
  • Substance dependency

  • Nicotine dependency and smoking cessation
  • Alcoholism
  • Hepatitis
  • Could Big Sugar become the next Big Tobacco?
  • What gets ignored in the pot debate: it's not good for you!
  • Surgery

  • Supplements for surgery
  • Dr. Hoffman lists the supplements he takes for his broken hip
  • Supplements and surgery: what you need to know (part one)
  • Supplements and surgery: what you need to know (part two)
  • Underweight and malabsorption

  • Do you have SIBO (Small Intestinal Bacterial Overgrowth)?
  • Underweight and malabsorption
  • Urinary tract disorders

  • D-mannose: an aid in ameliorating urinary tract infections
  • Kidney stones: treatment and prevention
  •