Methyl-Guard Plus

by Thorne Research


Product Information

Methylation - the addition of a methyl group (CH4 - one carbon attached to three hydrogens) to another molecule is an essential and vital biochemical process within the human body that is involved in a large number of biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. A number of specific nutrients are necessary for methylation to occur normally.

Methyl-Guard Plus contains higher amounts of 5-MTHF (the active form of folate), pyridoxal 5'-phosphate (active B6), and methylcobalamin (active B12), than our original Methyl-Guard. We have also added riboflavin 5'-phosphate (the active form of vitamin B2) for its positive effect on homocysteine metabolism and methylation.* These ingredients provide the necessary nutrients the body uses to push forward the process of methylation. Methyl-Guard Plus is more concentrated, so your patients will appreciate the recommended daily amount of three capsules, which will improve compliance. Our original Methyl-Guard is still available.

  • contains higher amounts of 5-MTHF (active folate), B6, B12

  • riboflavin 5'-phosphate added for extra homocysteine metabolism support

  • easy 3 capsules daily dosing


Three capsule contain: Riboflavin (as Riboflavin 5'-Phosphate Sodium) 90 mg, Vitamin B6 (as Pyridoxal 5'-Phosphate) 45 mg, Folate (as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 3 mg, Vitamin B12 (as Methylcobalamin) 3 mg, Betaine Anhydrous (Trimethylglycine) 1,800 mg.

Other ingredients: Hypromellose (derived from cellulose) capsule, Calcium Citrate, Calcium Laurate.

Suggested use: Take 1-3 capsules daily or as recommended by a health-care practioner.


The information and product descriptions appearing on this website are for information purposes only, and are not intended to provide medical advice to individuals. Consult with your physician if you have any health concerns, and before initiating any new diet, exercise, supplement, or other lifestyle changes.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

90 capsules


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